科学研究

科学进展

邹鹏课题组在《Cell Reports Methods》发表题为“Functional imaging-guided cell selection for evolving genetically encoded fluorescent indicators”的研究论文，报道了基于荧光成像的定向进化方法Faculae，实现了遗传编码远红色钙探针的多维度表型筛选与定向进化。
王韵课题组在《Cancer Letters》发表题为“CDYL knockdown reduces glioma development through an antitumor immune response in the tumor microenvironment”的研究论文。文章以胶质瘤最常见的组织细胞学类型星形胶质细胞瘤来源的临床样本组织和细胞系为研究对象，揭示了CDYL在胶质瘤发生发展...
方方课题组在《Current Biology》合作发表题为“Dyadic visual perceptual learning on orientation discrimination”的研究论文，运用功能磁共振脑成像与心理物理学实验，首次揭示了社会情境对于视觉知觉学习的促进作用以及相关的神经加工机制。
王征实验室在《Cell Reports》发表题为“Noncoding transcripts are linked to brain resting-state activity in non-human primates”的研究论文，报道了利用实验室前期收集的猕猴全脑分区、单细胞转录组图谱和静息态脑影像数据，整合分析发现150个非编码基因与蛋白编码基因一起共同调控大脑网络在静息状态下的同步自发振...
纳家勇治课题组在《PLOS Biology》期刊上发表题为“Sequential involvements of the perirhinal cortex and hippocampus in the recall of item-location associative memory in macaques”的研究论文，通过猕猴电生理研究揭示了语义记忆提取的两段式机制。方位记忆信息先由鼻周皮质...
岳伟华课题组在《Military Medical Research》在线发表了题为“Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis”的研究，发现并验证了...
岳伟华课题组在《Psychiatry and Clinical Neurosciences 》发表题为“Therapeutic Outcomes Wide Association Scan of different antipsychotics in patients with schizophrenia: randomized clinical trials and multi-ancestry...
邹鹏课题组在《Nature Communications》发表题为“Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome”的研究论文，报道了一种基因编码的可见光催化时空分辨蛋白质组邻近标记新技术。
黄卓课题组在《eLife》期刊在线发表了题为“Coupling of Slack and Nav1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development”的研究成果，发现电压门控钠离子通道Nav1.6和钠离子激活的钾离子通道Slack之间的功能和物理耦连，两通道耦连显著增强了Sla...
陈良怡课题组在《Nature Communications》发表了题为“Quantitative structured illumination microscopy via a physical model-based background filtering algorithm reveals actin dynamics”的研究论文。通过仔细研究结构光显微镜的成像过程，提出基于物理成像模型的...