题目：Studying neural circuits mediating fear and anxiety in zebrafish brain

报告人：Emre Yaksi Ph.D. Director / Group Leader - Neuroelectronics Research Flanders, Belgium; ( Assistant Professor - Neurophysiology Department - KU Leuven, Belgium )

时间：2013年06月24日 星期一 10:30-11:30

地点： 金光生命科学大楼208室

联系人：李毓龙研究员

摘要:

The habenula (HB) is a highly conserved brain region, which connects the forebrain and the limbic system to monoaminergic brainstem nuclei. HB is organized into anatomically distinct sub-regions which innervate different brainstem target areas, releasing dopamine, serotonin and acetylcholine. Genetic ablation of HB in zebrafish and HB lesions in rats perturb experienced depended fear response. Thus understanding Hb computations are important for understanding the neural correlates of stress, fear and anxiety.  In my presentation I will present our results on functional and topographically organization of HB networks of zebrafish, using two photon calcium imaging, electrophysiology and animal behavior. I will discuss about the contribution of these networks on how animals process sensory information, compare this information to their internal states and generate behaviors.